MTHFR C677T and A1298C polymorphism’s effect on risk of colorectal cancer in Lynch syndrome

- Wiik, Mariann Unhjem, Negline, Mia, Klinkhammer, Hannah, Spier, Isabel, Perne, Claudia, Mayr, Andreas, Valle, Laura, Lubinski, Jan, Sjursen, Wenche, Scott, Rodney J., Talseth-Palmer, Bente A., Beisvåg, Vidar, Clapham, Matthew, Holliday, Elizabeth, Dueñas, Nuria, Brunet, Joan, Pineda, Marta, Bonifaci, Nuria, Aretz, Stefan

Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

- Moller, Pal, Seppala, Toni, Capella, Gabriel, Poplawski, N, Hoogerbrugge, N, Morrison, PJ, James, P, Lee, G, Chen-Shtoyerman, R, Ankathil, R, Pai, R, Ward, R, Parry, S, Evans, Dafydd Gareth, Debniak, T, John, T, van Overeem Hansen, T, Caldes, T, Yamaguchi, T, Barca-Tierno, V, Garre, P, Cavestro, GM, Weitz, J, Redler, S, Burn, John, Buettner, R, Heuveline, V, Hopper, JL, Win, AK, Lindor, N, Gallinger, S, Le Marchand, L, Newcomb, PA, Figueiredo, J, Buchanan, DD, Holinski-Feder, Elke, Thibodeau, SN, ten Broeke, SW, Hovig, E, Nakken, S, Pineda, M, Duenas, N, Brunet, J, Green, K, Lalloo, F, Newton, K, Bertario, Lucio, Crosbie, EJ, Mints, M, Tjandra, D, Neffa, F, Esperon, P, Kariv, R, Rosner, G, Pavicic, WH, Kalfayan, P, Torrezan, GT, Bonanni, Bernardo, Bassaneze, T, Martin, C, Moslein, G, Ahadova, A, Kloor, M, Sampson, JR, Jenkins, MA, Lindblom, Annika, Levi, Zohar, Macrae, Finlay, Winship, Ingrid, Dowty, James G., Plazzer, John-Paul, Sijmons, R, Laghi, L, Della Valle, A, Heinimann, K, Half, E, Lopez-Koestner, F, Alvarez-Valenzuela, K, Scott, Rodney J., Katz, L, Haupt, Saskia, Laish, I, Vainer, E, Vaccaro, CA, Carraro, DM, Gluck, N, Abu-Freha, N, Stakelum, A, Kennelly, R, Winter, D, Rossi, BM, Dominguez-Valentin, Mev, Greenblatt, M, Bohorquez, M, Sheth, H, Tibiletti, MG, Lino-Silva, LS, Horisberger, K, Portenkirchner, C, Nascimento, I, Rossi, NT, da Silva, LA, Sunde, Lone, Thomas, H, Zarand, A, Mecklin, J-P, Pylvanainen, K, Renkonen-Sinisalo, L, Lepisto, A, Peltomaki, P, Therkildsen, C, Lindberg, LJ, Thorlacius-Ussing, O, Bernstein, Inge, von Knebel Doeberitz, M, Loeffler, M, Rahner, N, Steinke-Lange, V, Schmiegel, W, Vangala, D, Perne, C, Hueneburg, R, de Vargas, AF, Latchford, A, Engel, Christoph, Gerdes, A-M, Backman, A-S, Guillen-Ponce, C, Snyder, C, Lautrup, CK, Amor, D, Palmero, E, Stoffel, E, Duijkers, F, Hall, MJ, Aretz, Stefan, Hampel, H, Williams, H, Okkels, H, Lubinski, J, Reece, J, Ngeow, J, Guillem, JG, Arnold, J, Wadt, K, Monahan, K, Nielsen, Maartje, Senter, L, Rasmussen, LJ, van Hest, LP, Ricciardiello, L, Kohonen-Corish, MRJ, Ligtenberg, MJL, Southey, M, Aronson, M, Zahary, MN, Samadder, NJ

Lynch syndrome testing of colorectal cancer patients in a high-income country with universal healthcare: a retrospective study of current practice and gaps in seven australian hospitals

- Steinberg, Julia, Chan, Priscilla, Pearn, Amy, Nichols, Cassandra, McKay, Skye, Hayward, Anne, Egoroff, Natasha, Engel, Alexander, Gibbs, Peter, Goodwin, Annabel, Harris, Marion, Kench, James G., Hogden, Emily, Pachter, Nicholas, Parkinson, B, Pockney, Peter, Ragunathan, A, Smyth, C, Solomon, M, Steffens, D, Toh, JWT, Wallace, M, Canfell, K, Tiernan, Gabriella, Gill, A, Macrae, F, Tucker, K, Taylor, N, Morrow, April, Kang, Yoon-Jung, He, Emily, Venchiarutti, Rebecca, Titterton, Leanna, Sankey, Lucien

Modifier genes and Lynch syndrome: some considerations

- Scott, Rodney J.

Comparing theory and non-theory based implementation approaches to improving referral practices in cancer genetics: a cluster randomised trial protocol

- Morrow, April, Hogden, Emily, Wolfenden, Luke, Mitchell, Gillian, Macrae, Finlay, Tucker, Kathy, Taylor, Natalie, Kan, Yoon-Jung, Canfell, Karen, Solomon, Michael J., Kench, James G., Gill, Anthony J., Shaw, Tim, Pachter, Nicholas, Parkinson, Bonny

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report

- Seppala, Toni T., Ahadova, Aysel, Bernstein, Inge, Holinski-Feder, Elke, Pylvanainen, Kirsi, Renkonen-Sinisalo, Laura, Lepisto, Anna, Lautrup, Charlotte Kvist, Lindblom, Annika, Plazzer, John-Paul, Winship, Ingrid, Tjandra, Douglas, Dominguez-Valentin, Mev, Katz, Lior H., Aretz, S, Hueneburg, R, Holzapfel, S, Heinimann, K, Della Valle, A, Neffa, F, Gluck, N, Cappel, WHDVTN, Vasen, H, Macrae, Finlay, Morak, M, Steinke-Lange, V, Engel, C, Rahner, N, Schmiegel, W, Vangala, D, Thomas, H, Green, K, Lalloo, F, Crosbie, EJ, Evans, D. Gareth, Hill, J, Capella, G, Pineda, M, Navarro, M, Blanco, I, ten Broeke, S, Nielsen, M, Ljungmann, K, Nakken, S, Lindor, N, Therkildsen, Christina, Frayling, I, Hovig, E, Sunde, L, Kloor, M, Mecklin, J-P, Kalager, M, Moller, P, Sampson, Julian, Scott, Rodney, Burn, John, Moeslein, Gabriela

Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report

- Dominguez-Valentin, Mev, Seppälä, Toni T., Sampson, Julian R., Macrae, Finlay, Winship, Ingrid, Evans, D. Gareth, Scott, Rodney J., Burn, John, Möslein, Gabriela, Bernstein, Inge, Pylvänäinen, Kirsi, Renkonen-Sinisalo, Laura, Lepistö, Anna, Lindblom, Annika, Plazzer, John-Paul, Tjandra, Douglas, Thomas, Huw, Green, Kate, Lalloo, Fiona, Crosbie, Emma J.

Lessons learnt from implementation of a Lynch syndrome screening program for patients with gynaecological malignancy

- Najdawi, Fedaa, Crook, Ashley, Sioson, Loretta, Ahadi, Masha, Turchini, John, Clarkson, Adele, Hogg, Russell, Valmadre, Sue, Gard, Greg, Dooley, Susan J., Scott, Rodney J., Fox, Stephen B., Maidens, Jayne, Field, Michael, Gill, Anthony J., McEvoy, Christopher, Fellowes, Andrew, Pickett, Justine, Ho, Musei, Nevell, David, McIlroy, Kirsten, Sheen, Amy

New EPCAM founder deletion in Polish population

- Dymerska, D., Gołębiewska, K., Szwiec, M., Kilar, E., Huzarski, T., Byrski, T., Lubiński, J., Kurzawski, G., Kuświk, M., Rudnicka, H., Scott, R. J., Billings, R., Pławski, A., Boruń, P., Siołek, M., Kozak-Klonowska, B.

Use of multigene-panel identifies pathogenic variants in several CRC-predisposing genes in patients previously tested for Lynch Syndrome

- Hansen, Maren F., Johansen, Jostein, Sjursen, Wenche, Sylvander, Anna E., Bjørnevoll, Inga, Talseth-Palmer, Bente A., Lavik, Liss A. S., Xavier, Alexandre, Engebretsen, Lars F., Scott, Rodney J., Drabløs, Finn

Early changes of endometrial neoplasia revealed by loss of mismatch repair gene protein expression in a patient diagnosed with Lynch syndrome (letter)

- McKenzie, Ross, Scott, Rodney J., Otton, Geoffrey, Scurry, James

Management of ovarian and endometrial cancers in women belonging to HNPCC carrier families: review of the literature and results of cancer risk assessment in Polish HNPCC families

- Dębniak, Tadeusz, Gromowski, Tomasz, Cybulski, Cezary, Serrano-Fernandez, Pablo, Lubiński, Jan, Scott, Rodney J., Gronwald, Jacek, Huzarski, Tomasz, Byrski, Tomasz, Kurzawski, Grzegorz, Dymerska, Dagmara, Górski, Bohdan, Paszkowska-Szczur, Katarzyna

Obesity, aspirin, and risk of colorectal cancer in carriers of hereditary colorectal cancer: a prospective investigation in the CAPP2 study

- Movahedi, Mohammad, Bishop, D. Timothy, Bisgaard, Marie-Luise, Dunlop, Malcolm G., Ho, Judy W. C., Hodgson, Shirley V., Lindblom, Annika, Lubinski, Jan, Morrison, Patrick J., Murday, Victoria, Ramesar, Raj S., Side, Lucy, Macrae, Finlay, Scott, Rodney J., Thomas, Huw J. W., Vasen, Hans F., Burn, John, Mathers, John C., Mecklin, Jukka-Pekka, Moeslein, Gabriela, Olschwang, Sylviane, Eccles, Diana, Evans, D. Gareth, Maher, Eamonn R., Bertario, Lucio

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

- Thompson, Bryony A., Spurdle, Amanda B., du Sart, Desiree, Fabre, Aurelie, Farrell, Michael P., Farrington, Susan M., Frayling, Ian M., Frebourg, Thierry, Goldgar, David E., Heinen, Christopher D., Holinski-Feder, Elke, Kohonen-Corish, Maija, Plazzer, John-Paul, Robinson, Kristina Lagerstedt, Leung, Suet Yi, Martins, Alexandra, Moller, Pat, Morak, Monika, Nystrom, Minna, Peltomaki, Paivi, Pineda, Marta, Qi, Ming, Ramesar, Rajkumar, Greenblatt, Marc S., Rasmussen, Lene Juel, Royer-Pokora, Brigitte, Scott, Rodney J., Sijmons, Rolf, Tavtigian, Sean V., Tops, Carli M., Weber, Thomas, Wijnen, Juul, Woods, Michael O., Macrae, Finlay, Akagi, Kiwamu, Genuardi, Maurizio, Al-Mulla, Fahd, Bapat, Bharati, Bernstein, Inge, Capellá, Gabriel, den Dunnen, John T.

Cell cycle-related genes as modifiers of age of onset of colorectal cancer in Lynch syndrome: a large-scale study in non-Hispanic white patients

- Chen, Jinyun, Pande, Mala, Scott, Rodney J., Frazier, Marsha L., Huang, Yu-Jing, Wei, Chongjuan, Amos, Christopher I., Talseth-Palmer, Bente A., Meldrum, Cliff J., Chen, Wei V., Gorlov, Ivan P., Lynch, Patrick M.

Genetic modifiers of cancer risk in Lynch syndrome: a review

- Talseth-Palmer, Bente A., Wijnen, Juul T., Grice, Desma M., Scott, Rodney J.

8q23.3 and 11q23.1 as modifying loci influencing the risk for CRC in Lynch syndrome

- Talseth-Palmer, Bente A., Scott, Rodney J., Vasen, Hans F. A., Wijnen, Juul T.

DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome

- Reeves, Stuart G., Meldrum, Cliff, Groombridge, Claire, Spigelman, Allan, Suchy, Janina, Kurzawski, Grzegorz, Lubinski, Jan, Scott, Rodney J.

Modifier genes in Lynch syndrome: functional genomics and its consequence on disease expression

- Reeves, Stuart

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

- Burn, John, Gerdes, Anne-Marie, Bisgaard, Marie Louise, Dunlop, Malcolm G., Ho, Judy W. C., Hodgson, Shirley V., Lindblom, Annika, Lubinski, Jan, Morrison, Patrick J., Murday, Victoria, Ramesar, Raj, Side, Lucy, Macrae, Finlay, Scott, Rodney J., Thomas, Huw J. W., Vasen, Hans F., Barker, Gail, Crawford, Gillian, Elliott, Faye, Movahedi, Mohammad, Pylvanainen, Kirsi, Wijnen, Juul T., Fodde, Riccardo, Mecklin, Jukka-Pekka, Lynch, Henry T., Mathers, John C., Bishop, D. Timothy, Moeslein, Gabriela, Olschwang, Sylviane, Eccles, Diane, Evans, D. Gareth, Maher, Eamonn R., Bertario, Lucio